Published at PsychedelicFinance.com
This is an area of research with research barriers imposed for quite some time. We see now changes in policy and attitudes, which will enable us to bring modern drug discovery into the field and move it forward with exciting discoveries and new therapies.
It has been disappointing to see the slow progress in traditional CNS (Central Nervous System) therapeutics approaches as practiced in pharma. The psychedelic natural products give us alternative approaches and can address unmet needs that have stymied CNS therapeutics. I’m very optimistic with the progress that has been made in psychedelics and anticipate incredible growth in this area.
Adapting any compound for clinical use requires one to understand the drug on a molecular level and anticipate development issues such as manufacture, stability, formulation, off-target effects and safety. Through the application of the principles of medicinal chemistry, we can address these issues and develop a product clinicians can use confidently.
I was impressed with the competence and depth of the Mydecine team and my working with them has been completely enjoyable. They are working with major players in the field of psychedelics research and the team is able to identify new opportunities for collaboration and engagement. Currently, I am taking a deep look at psychedelics of interest to Mydecine, identifying new opportunities, developing intellectual property and setting research strategies.
As anyone in research will tell you, the efficacy of an agent can be complex on a receptor level and deciphering mechanisms of action responsible for any therapeutic effect challenging. Fortunately, the psychedelics have a deep history of past anecdotal use that informs more rigorous studies. This is a key advantage in providing strong proof of concept for particular indications.
Past policy on the utility of psychedelics has been confused with dirty drugs, recreational abuse and unscientific conclusions made for political and societal reasons. Bringing serious study with well characterized agents is needed to make progress in identifying the appropriate illnesses and clinical environments in which effective treatments can be developed.
The psychedelics we are currently focusing on have clear indications for specific illnesses and that provides our short term focus and growth. However, we believe there are many new opportunities to expand the use of psychedelics and the time is ripe to begin the research. We are able to anticipate potential issues that can hinder the development of psychedelics and find solutions. This includes the invention of new molecular entities and is the long view. Taking this long view will drive new discoveries and open up the field of CNS research.
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